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Contraindicated (1)pentobarbital will minimize the extent or effect of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with potent CYP3A4 inducers may result in reduced serum concentrations and lack of antimalarial efficacypentobarbital will reduce the level or effect of alosetron by influe